Pyridine aldehydes are typically prepared by oxidation of. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032 phone. Workers who make or use the chemical may be exposed to higher levels of it. The major use of pyridine, alkyl derivatives is as a corrosion inhibitor of oil and gas wells and pipelines in canada. This information should be helpful to those that need to get the information quickly. This fact sheet is one in a series of summaries about hazardous substances and their health effects. Product identifier product name pyridinenoxide product number fp01239 cas number 694597 ec number 2117746 1. It is used as a solvent for paints, rubber, dyes and resins. The intent is not to provide an exhaustive list of analytical methods that could be used to detect and quantify pyridine. Pyridine general information key points pyridine is a colourless flammable liquid with a strong and unpleasant fishlike odour it is used as a solvent for paints, rubber, dyes and resins a small amount of pyridine may occur naturally in the environment. Pyridine is a lewis base, donating its pair of electrons to a lewis acid. Central drug house p ltd 728 vardaan house new delhi2 india. Pyridinebarbituric acid reagent safety data sheet according to federal register vol. Pyridine acs safety data sheet according to the federal final rule of hazard communication revised on 2012 hazcom 2012 jubilant life sciences limited page 3 of 10 with the aid of a pocket mask equipped with a oneway valve or other proper respiratory medical device.
Msds 0296a00 div 05 msds 42nitroanilino pyridine page 1 of 5 ref. Pyridine has a very noticeable and unpleasant smell, and even small quantities can make the working environment intolerable. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. It serves as a precursor to other compounds of interest in coordination chemistry and pharmaceuticals. Copper chloridepyridine reagent shelf life on ship date. It is a colorless oily liquid with a distinctive odor. Analytical methods the purpose of this chapter is to describe the analytical methods that are available for detecting andor measuring and monitoring pyridine in environmental media and in biological samples. The simplest member of the pyridine family is pyridine itself, a compound with molecular formula c 5 h 5 n pyridine is used as a solvent and is added to ethyl alcohol to make it unfit for drinking. Pyridine, any of a class of organic compounds of the aromatic heterocyclic series characterized by a sixmembered ring structure composed of five carbon atoms and one nitrogen atom.
Page 2 of 4 section 4 first aid measures use good personal hygiene practices. Many pyridines of commercial interest find application in market areas where bioactivity is important, as in medicinal drugs and in agricultural products. This chemical has been found in at least 11 of 1,416 national priorities list sites identified by the environmental protection agency. Msds 0296a00 div 05 msds 42nitroanilinopyridine page 1 of 5 ref. Its complexes having tetrahedral and octahedral geometries can be differentiated by infrared spectral investigations. Pyridine noxide according to regulation ec no 19072006, annex ii, as amended. Aquametric is a complete solution for all laboratories that carry out water content of a sample as it also includes water standards, working mediums and dry solvents for some specific. Older samples are often browncolored owing to impurities. Pyridine acs safety data sheet according to the federal final. Heating from this acidbase reaction led to an explosion and fire mca case history 1284 1967. Pyridine, alkyl derivatives is an industrial chemical. Pyridine is produced from natural sources such as coal tar or by chemical synthesis.
Piperidine safety data sheet according to the federal. Further details of the study were unavailable from the database. No 0296a00 div 05 msds 42nitroanilino pyridine jubilant organosys limited date of issue. Pyridine noxide is the pyridine noxide derived from the parent pyridine. Species human 79912, species mouse 232491, species rat 297708, species chicken 418191, species domestic cat 101088088, species dog 477678, species cow 505859, species sheep 101119461, species domestic guinea pig 100719418, species naked molerat. Pyridine is widely used as a solvent in organic chemistry and in industrial practice. It is a highly flammable, weakly alkaline, watermiscible liquid with a distinctive, unpleasant fishlike smell. If in a laboratory setting, follow chemical hygiene plan. This material does not contain any hazardous air pollutants. Precautions for safe handling precautions for safe handling. P280 wear eye protection, face protection, protective clothing, protective gloves. Mar 03, 2011 this fact sheet answers the most frequently asked health questions about pyridine. Chemical product and company identification product name. Pyridine goes into the production of piperidine harper et al.
It is also used as a solvent for paint, rubber, pharmaceuticals. Studies in people and animals suggest that pyridine may damage the liver. Pyridineborane c 5 h 5 nbh 3, melting point 1011 c is a mild reducing agent. Karl fischer reagent material safety data sheet sdsmsds. Pyridine is known to reduce male fertility and chronic exposure may cause serious harm. Not classifiable as to its carcinogenicity to humans pyridine. It is structurally related to benzene, with one methine group ch. P271 use only outdoors or in a wellventilated area. Pyridine adsorbs to colloidal particles of sodium montmorillonite and kaolinite, a process which is attributed to cation exchange and is a function of ph5. Ntp no components of this product present at levels greater than or equal to 0. Material safety data sheet pyridine msds section 1. For more information, you may call the atsdr information center at 18002324636.
Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work. Adsorption is at a minimum at ph 1 and 11 and reaches a maximum at ph 4 for the montmorillonite and ph 5. Use water spray to cool fire exposed tanks and containers. Pyridine py may be used in the preparation of vanadium oxide nanoparticles and iron benzenedicarboxylates.
Identification of the substancemixture and of the companyundertaking 1. Pyridine, anhydrous 110861 p1689 spectrum chemical. Pyridine is a basic heterocyclic organic compound with the chemical formula c 5 h 5 n. The major use of pyridine, alkyl derivatives is as a corrosion inhibitor of oil and gas wells and pipelines. Pyridinenoxide according to regulation ec no 19072006, annex ii, as amended. Pyridine acs safety data sheet according to the federal. Pyridine is an azaarene comprising a benzene core in which one ch group is replaced by a nitrogen atom. Safety data sheet according to 29cfr19101200 and ghs rev. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene, an azaarene and a member of pyridines. Everyone is exposed to very low levels of pyridine in air, water, and food. The simplest member of the pyridine family is pyridine itself, a compound with molecular formula c5h5n. Sigmaaldrich 270970 page 1 of 7 sigmaaldrich material safety data sheet version 4.
Wear chemical protective suit with selfcontained breathing apparatus. Pyridine is an effective, basic solvent that is relatively unreactive, which makes it a good acid scavenger. If breathing stops, provide artificial respiration. Pyridine is also used as an intermediate in the preparation of drugs. Pyridine is the solvent of choice for acylation and dehydrochlorination reactions. During preparation of a complex of pyridine with chromium trioxide, an acid, the proportion of chromium trioxide was increased. Product identifier product name pyridine noxide product number fp01239 cas number 694597 ec number 2117746 1. If skin contact should occur, material should be washed away with a mild soap and water. Box 2650 tulsa, oklahoma 74101 for emergency source information contact. It acts as nitrogen donor ligand and forms many metalpyridine complexes. Inhalation remove person to fresh air and keep comfortable for breathing.
It is a drug metabolite of the antihypertensive agent pinacidil. It acts as nitrogen donor ligand and forms many metal pyridine complexes. Toxicology and carcinogenesis studies of pyridine cas no. Chemtrec 8004249300 outside usa 7035273887 1216 6th ave n kent wa 98032. Commission regulation eu no 2015830 of 28 may 2015. Piperidine safety data sheet according to the federal final rule of hazard communication revised on 2012 hazcom 2012 jubilant life sciences limited page 3 of 8 withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. Pyridine, anhydrous is a heterocyclic organic compound most often used as a precursor to pharmaceuticals and agrochemicals, as well as a reagent and a solvent. One example is the sulfur trioxide pyridine complex melting point 175 c, which is a sulfation agent used to convert alcohols to sulfate esters. Pyridine is colorless, but older or impure samples can appear yellow. Sigmaaldrich 3050 spruce street saint louis mo 63103 usa.
Safety data sheets sections 1 through 8 contain general information about the chemical, identification, hazards, composition, safe handling practices, and emergency control measures e. Anhydrous, dry, without water, is used when performing certain reactions where the presence of water can prevent a chemical reaction from happening, or form undesirable products. Description of first aid measures general information get medical adviceattention if you feel unwell. It is also used to produce a variety of different products including other industrial chemicals, pesticides, herbicides, fungicides. Acetone safety data sheet according to federal register vol. Pyridine barbituric acid reagent safety data sheet according to federal register vol. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Check availability and compare product details pyridine chromasolv plus, for hplc. Revised on 08102015 page 5 of 6 respiratory lc50 inhalation rat 1 h 28,500 mgm3 ingestion ld50 oral rat 891. It should be handled, wearing gloves, in a fume cupboard. No 0296a00 div 05 msds 42nitroanilinopyridine jubilant organosys limited date of issue. Aquametric is the range of pyridinefree karl fischer reagents from panreac applichem for volumetric and coulometric determination of water. Pyridine prd cautionary response information common synonyms liquid colorless to yellow sharp, nauseating odor mixes with water.
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